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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM154
All Species:
4.55
Human Site:
S174
Identified Species:
14.29
UniProt:
Q6P9G4
Number Species:
7
Phosphosite Substitution
Charge Score:
0.43
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P9G4
NP_689893.1
183
20498
S174
T
L
K
E
E
K
E
S
N
H
N
P
S
D
S
Chimpanzee
Pan troglodytes
XP_517484
183
20466
S174
T
L
K
E
E
K
E
S
N
H
N
P
S
D
S
Rhesus Macaque
Macaca mulatta
XP_001085886
103
11608
N95
L
K
E
E
K
E
S
N
H
N
P
S
D
N
E
Dog
Lupus familis
XP_855280
603
65368
E199
L
L
D
T
A
L
R
E
A
T
I
S
P
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C4Q9
181
19861
P172
T
L
K
E
E
K
E
P
N
P
S
P
S
D
N
Rat
Rattus norvegicus
NP_001102023
167
18310
P158
T
L
K
E
E
K
E
P
N
L
S
P
S
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001234848
194
20575
E184
T
V
R
E
E
E
K
E
S
V
A
N
P
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663110
182
20348
E151
K
V
P
M
P
M
F
E
D
D
I
P
S
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
53.5
20.2
N.A.
64.4
52.4
N.A.
N.A.
38.1
N.A.
27.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
55.7
24
N.A.
73.2
66.1
N.A.
N.A.
51.5
N.A.
47.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
73.3
73.3
N.A.
N.A.
20
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
53.3
6.6
N.A.
86.6
86.6
N.A.
N.A.
53.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
13
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
13
13
0
0
13
50
13
% D
% Glu:
0
0
13
75
63
25
50
38
0
0
0
0
0
0
25
% E
% Phe:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
13
25
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
25
0
0
0
0
% I
% Lys:
13
13
50
0
13
50
13
0
0
0
0
0
0
0
0
% K
% Leu:
25
63
0
0
0
13
0
0
0
13
0
0
0
0
0
% L
% Met:
0
0
0
13
0
13
0
0
0
0
0
0
0
0
13
% M
% Asn:
0
0
0
0
0
0
0
13
50
13
25
13
0
13
25
% N
% Pro:
0
0
13
0
13
0
0
25
0
13
13
63
25
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
13
0
0
0
13
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
13
25
13
0
25
25
63
25
25
% S
% Thr:
63
0
0
13
0
0
0
0
0
13
0
0
0
0
0
% T
% Val:
0
25
0
0
0
0
0
0
0
13
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _